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Inform patients of the risk of CRS and to immediately contact their healthcare professional should signs and symptoms associated with CRS, for example, pyrexia, hypotension, hypoxia, chills, tachycardia, headache, dyspnea, occur at any time

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237 In a study in mice, zingerone (an active compound from ginger) inhibited not only platelet aggregation but also the activity of factor Xa, an enzyme in the clotting cascade